The Ambrosiana University has edited a treatise on SARS-COV 2 by Professor Giuseppe R.Brera, director of the Milan  School of Medicine  and president of the International Committee for the change of the paradigm of health and medicine. The treatise introduces into virology the revolutionary physiological concept of “Allostasis”, hitherto unknown to most virologists, clinicians and researchers, and recently the subject of an international conference on its importance for the paradigmatic change of medicine. The treatise, the first in the world, addresses the scientific and clinical approach to infection in a new multifactorial perspective, integrating the experimental and clinical investigations of SARS-COV and SARS-COV 2 in virology, immunology, epidemiology biochemistry. This impressive theoretical work on more than 1000 experimental and clinical investigations since 2002, forms the basis of a new approach to the pandemic called: “Person-Centered Prevention and Infection Early Treatment according to “Person-Centered Medicine”, which since 1999 has revolutionized medicine and medical science and since then taught at the School of Medicine in Milan.

In the treatise, Prof. Brera introduces the theory of relativity of virus entry into cells through an alteration of the membrane structure induced by cholesterol and the consequences, even fatal, of infection, due to atherosclerosis resulting in innate and adaptive immunity depression and an abnormal reaction induced by the immune phenotype to viral antigen stimuli. The theory explains the vulnerability of patients with co-morbidity characterized by atherosclerosis and the innate immune protection of children and young people (up to 30 ) who do not need any vaccination.

The entry of the virus into cells  is conditioned by the “lipid rafts” where the virus with the ACE 2 receptors and other transmigrates for endocytosis..

The signal deviation induced by LDL cholesterol in the “lipid rats” of atherosclerotic patients induces an immune phenotype favoring the fatal immune anergy after the seventh day easily detectable and preventable, strategy so far omitted with a fatal error of the WHO and most health governments of the countries, error paid by millions of people.

The theory of the relativity of SARS-COV 2 infection is crucial to change the prevention strategy and free humanity from the nightmare of SARS-COV 2 and its variants. It allows for the preventive detection of people vulnerable to infection and directs to primary and secondary prevention based on the reinforcement of immunity, a strategy omitted by the fatal ignorance of public health managers that caused more than a million deaths. Epistemological and scientific illiteracy has been paid by the world and Italian population but has been well supported and practiced by most of the world governments and the WHO. In Italy, this is the main cause of the request of the “National Health Committee” for determined action to induce the resignation of the Minister of Health Roberto Speranza.

The treatise was preceded by another book by the same author, Person-Centered Medicine and Person-Centered Clinical Method, the application of which leads to saving people’s suffering and the health costs of countries in a meaningful way as it appears from the data published in the book. Here the author also presented the epistemological basis of the new concept of health, and a chapter highlights the necessary pathways of entry of SARS-COV and the development of COVID-19 , also discussing the scientific probability of induction of cancer of vaccines against SARS-COV mRNA. This essay and the treatise are a crucial contribution to addressing any prevention and treatment of any pandemic, underpinning the strategy of the “Person-Centred Prevention Programme””, which orients public health to health promotion, education, health education, self-treatment and induced cross-prevention with other communicable and non-communicable diseases.

These books indicate that the most dangerous pandemic seems to be epistemological ignorance of the changing paradigm of Medicine..  This delay has led to a mono-dimensional, failed  virological approach to the pandemic, aimed only at inducing mechanistic prevention-wrong biotechnology and human rights violations and an economic failure of the countries that is causing the poverty of millions of people. The establishment by Europe and some European countries of a “Green Pass” for vaccinated people is without any scientific foundation because vaccination does not prevent infections and contagion.  Vice versa,  from 2002 to 2020, the multinational vaccines have not produced any vaccine because of the frequent mutations of the virus. The theory of relativity SARS-COV 2 refutes the erroneous mechanistic-determinist  and linear causality model, in coping to COVID-19 promoted by the WHO and many countries, omitting secondary prevention. This wrong approach caused more than a million deaths because it pushed primary prevention only to biotechnological measures, excluding people’s health education to an immuno-empowering and anti-viral quality of life. This omission based on ignorance gets to expose children and young people, completely protected by innate immunity, or elderly immunosenescent, with innate and adaptive immunity depression, to experimental vaccines with limited validity over time and completely useless against variants, with short and long-term risks of adverse effects until death.

The treatise is edited at the same time as the International Conference: for the 26th anniversary of the opening of the Ambrosiana University:

The paradigm shift centered on the person’s health and medicine paradigms and COVID-19

where the most significant  scientists contributors of the paradigms change of medicine and health explained the scientific basis of the transition from the dominant deterministic and one-dimensional paradigm-mechanistic to the new and its omission related to the development of the SARS-COV 2 pandemic.




Giuseppe R.Brera :Sars-Cov 2 allostasis and people and prevention centered on the person-A new prevention strategy based on the induction of people’s metabolic and immune shield for pandemic arrest COVID-19″ 632 p. – 1065 references.

First part: “The relativity of SARS-COV 2 entry and COVID 19 138 pp. euro 30 e-book and printed ISBN: 9798530093906


Giuseppe R.Brera: Person-Centered Medicine and Person-Centered Clinical Method- practical results of the paradigm of unitary medicine and the theory of prevention COVID-19 people and person-centered” – 131 p. -132 references euro 25 – e-book and print ISBN: 9798726465432


Distributed worldwide by Amazon and the editorial staff of the Ambrosiana University editorialdepartment@unambro.i

Re quest the Conference proceedings (free):






Lascia un commento

Il tuo indirizzo email non sarà pubblicato. I campi obbligatori sono contrassegnati *